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Mesenflow
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We recreate key aspects of inflammation (acute and chronic), allowing us to track how immune cells behave in real time as they interact with vascular and tissue environments.
Using bio-imaging and proprietary AI analysis, we generate high-resolution data that provide faster, cost-efficient and animal-free preclinical insights into compound safety, efficacy and mechanism of action. We help pharma and biotech increase predictive accuracy and reduce development risk across inflammation, oncology and toxicology.
01.
Recreate human inflammation in physiologically relevant systems
02.
Reduce reliance on animal testing in preclinical development
03.
Build tailored assays with strong translational value
04.
Continuously adapt our platform to meet real project needs
Generate
human-relevant data from the start
Identify
weaker candidates earlier in development
Reduce
cost and shorten development timelines
Focus
resources on the most promising compounds
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Cell Adhesion Model
Our adhesion model measures the strength of cell attachment using the controlled detachment assay, and static migration assay. This platform delivers reproductible analysis of cell adhesion dynamics starting with defined ligands through to migration dynamics in extravascular tissue models.
➔ Immune cell profiling
➔ Adhesion mechanism assessment
➔ Leukocyte kinetics in static tissue cocultures
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Inflammation Model
Our inflammation model recreates acute or chronic inflammatory states in human endothelial cells. This platform enables evaluation of compound efficacy and a reliable way to study inflammatory responses in a vascular micro-environment.
➔ Leukocytes trafficking
➔ Vascular modeling
➔ Mechanism of action (MoA)
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Tumor-Targeting Model
Our tumor-targeting model provides predictive insights into how immune cell activation drives anti-tumor efficacy. It enables precise assessment of immune-mediated tumor targeting in a human-relevant settings.
➔ CAR-T and B-cell therapies efficacy testing
➔ Cancer therapeutics and treatment
➔ Mechanisms of action (MoA)
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Organoid Model
Our vascularized organoid modelrecreates complex tissue micro-environments to study leukocyte trafficking and endothelial interactions. Integrating proprietary organoid components into our vascular models offers deeper insights into cell behavior and improves predictive power of preclinical studies.
➔ Tissue and vascular modeling
➔ Organ-specific drug testing
➔ Complex physiological interactions
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Our vision is to translate our platforms into tools that support clinical trials and personalized medicine, enabling researchers and clinicians to better understand patient-specific inflammatory responses and therapeutic outcomes.
MesenFlow Technologies SàrlChemin des Aulx 14
1228 Plan-les-Ouates
Geneva, Switzerland
+41 22 32 16 961 (office)
+41 79 36 66 291 (mobile)